All Abstracts

Redox signaling is how molecules, such as superoxide, communicate within cells to negatively impact normal cell function. Understanding redox signaling is important because of the role of redox signaling in the aging of a cell as a result of superoxide radicals. Superoxide Dismutase (SOD) is an anti...

Prostate cancer is the second leading cause of cancer deaths of males in the United States. Although it is usually treatable, advanced or metastatic prostate cancer can be mortal. Our laboratory examines the use of various diet-derived compounds as potential chemotherapeutic agents for advanced pros...

Prostate cancer is a multifocal disease, with varying sensitivity to hormone therapy or androgen deprivation therapy. It is initially responsive to therapies that inhibit androgen receptor (AR) signaling, but the disease eventually advances to an androgen-independent state. Investigators have demons...

Dibenzoylmethane (DBM) is a minor constituent of licorice root, a common ingredient in many sunscreens, and a known neoplasia inhibitor. Although DBM has exhibited anti-neoplastic activity in many studies, no reports offer definitive mechanisms of action for DBM on tumor growth inhibition. Our labor...